

Today, individualized medicines are possible.
We’re on a mission to make them safe and rapidly accessible to patients worldwide.
Today, individualized medicines are possible.
We’re on a mission to make them safe and rapidly accessible to patients worldwide.
As the field advances into a new era of interventional genetics, N1C is the professional home for practitioners to exchange knowledge, collaborate, set the tone for responsible innovation, and guide the standards that advance the field.
Our work takes shape across three pillars — knowledge, resources, and data — building the shared infrastructure needed to make individualized medicines globally accessible at scale.



Sharing Knowledge
Eight N1C Workgroups
Seminar Series
Podcast
Annual Meeting
Sharing Data
Gene Registry
Preclinical Database
Clinical Database
Open Forum
As the field advances into a new era of interventional genetics, N1C is the professional home for practitioners to exchange knowledge, collaborate, set the tone for responsible innovation, and guide the standards that advance the field.
Our work takes shape across three pillars — knowledge, resources, and data — building the shared infrastructure the field needs to make individualized medicines globally accessible and responsibly developed.

Sharing Knowledge
Eight N1C Workgroups
Seminar Series
Podcast
Annual Meeting
N1C VARIANT

Sharing Resources
Donated Resource Center
Publications
Workshops
Regulatory Guidances
Illustrated Examples

Sharing Data
Gene Registry
Preclinical Database
Clinical Database
Open Forum
N1C Annual Meeting 2026
Individual Journeys, Shared Discoveries:
Partnering for Progress in Individualized Medicine
Hyatt Regency Denver | Denver, CO | October 10, 2026
New FDA Draft Guidance
Plausible Mechanism Framework to Develop Individualized Therapies that Target Specific Genetic Conditions with Known Biological Cause
New MHRA Draft Rare Disease Therapies Regulatory Framework
A novel pathway for Investigational Marketing Authorisation
N1C Annual Meeting 2026
Individual Journeys, Shared Discoveries: Partnering for Progress in Individualized Medicine
Hyatt Regency Denver | Denver, CO | October 10, 2026
New FDA Draft Guidance
Plausible Mechanism Framework to Develop Individualized Therapies that Target Specific Genetic Conditions with Known Biological Cause
New MHRA Draft Rare Disease Therapies Regulatory Framework
A novel pathway for Investigational Marketing Authorisation
Next Seminar: NIH Platform Approaches for Monogenic Diseases
Join Dr. P.J. Brooks (NCATS/NIH) for a livestream on therapeutic platforms, gene therapy consortia, and advancements shaping individualized treatments.

Connections.
N1C’s platform for resources and member engagement
Connections is N1C’s virtual platform for community, collaboration, and shared resources. Here, you’ll find:
- Seminars and podcasts, guidelines,
publications, and community-built tools - Gene Registry: individualized therapy programs, assessed variants, and marketed gene therapies
- Donated Resource Center: in-kind goods and services for individualized programs

Connections.
N1C’s platform for resources and member engagement
Connections is N1C’s virtual platform for community, collaboration, and shared resources. Here, you’ll find:
- Seminars and podcasts, guidelines,
publications, and community-built tools - Gene Registry: individualized therapy programs, assessed variants, and marketed gene therapies
- Donated Resource Center: in-kind goods and services for individualized programs
Membership
N1C membership keeps you connected to the people and discussions shaping this field — and directly supports our collective mission. Members receive access to exclusive spaces on Connections, including:
- Patient Community: direct engagement with patients and families
- Research Community: field updates, collaborations, and funding opportunities
- Virtual Streaming: 2026 Annual Meeting
- Recording: 2025 Annual Meeting
- Direct messaging across the network


Membership
N1C membership keeps you connected to the people and discussions shaping this field — and directly supports our collective mission. Members receive access to exclusive spaces on Connections, including:
- Patient Community: direct engagement with patients and families
- Research Community: field updates, collaborations, and funding opportunities
- Virtual Streaming: 2026 Annual Meeting
- Recording: 2025 Annual Meeting
- Direct messaging across the network
*To become a member, you’ll first need to create a free account on Connections. Once registered, you can sign up for membership inside the platform.
*To become a member, you’ll first need to create a free account on Connections. Once registered, you can sign up for membership inside the platform.
Help Us Shape the Future of Individualized Medicines
Help Us Shape the Future of Individualized Medicines
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